| PAU = 0 | Breeding Colony/Stock - Animals held in breeding colonies (e.g., fish, rodents) that have not been assigned to a particular research, teaching or testing protocol. |
| PAU = 1 | Studies of a fundamental nature in sciences relating to essential structure or function (e.g., biology, psychology, biochemistry, pharmacology, physiology, etc.). |
| PAU = 2 | Studies for medical purposes, including veterinary medicine, that relate to human or animal disease or disorders. |
| PAU = 3 | Studies for regulatory testing of products for the protection of humans, animals, or the environment. |
| PAU = 4 | Studies for the development of products or appliances for human or veterinary medicine. |
| PAU = 5 | Education and training of individuals in post-secondary institutions or facilities. |
The CCAC requires institutional animal care committees (ACCs) to ensure that any potential pain and/or distress is minimized. Anesthetics and analgesics must be used; any exceptions require scientific justification and ACC approval.